There’s something comforting about the scent of buttery squash and bubbling cheese wafting from the oven. I’ve made this Southern Squash Casserole Recipe more times than I can count—it’s my go-to for holidays, Sunday suppers, and any time I need a cozy, golden-topped side that just makes people happy. It’s rich, savory, and every spoonful delivers that nostalgic Southern warmth.
What I love about this Southern Squash Casserole Recipe is how it transforms simple yellow squash into a show-stopping side. With the tender squash layered between creamy sauce and a crispy, cheesy topping, it’s practically begging for second helpings. If you’re looking for a way to win hearts at the dinner table, this recipe is it.
Why You’ll Love This Southern Squash Casserole
This Southern Squash Casserole Recipe checks all the boxes: it’s creamy, cheesy, and full of classic Southern flavor. It’s easy enough for weeknight meals but special enough to earn a spot on the holiday table. Whether you’re serving picky kids, comfort food lovers, or curious guests, this dish delivers with:
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Simple ingredients
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A crowd-pleasing cheesy top layer
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A versatile flavor that pairs with nearly any main dish
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The ability to make it ahead and reheat like a dream
What Kind of Squash Should I Use?
For this Southern Squash Casserole Recipe, yellow summer squash is the traditional and best choice. It has a mild, slightly sweet flavor and soft texture that becomes beautifully tender when baked. Look for squash that’s small to medium in size—they tend to have fewer seeds and better texture.
If you can’t find yellow squash, zucchini is the closest substitute in both texture and flavor. Just note that it may have a touch more moisture, so a light salting and draining before cooking can help keep the casserole from becoming watery.
Options for Substitutions
One of the reasons the Southern Squash Casserole Recipe is a beloved classic is because it’s so adaptable. Whether you’re adjusting for dietary needs or just using what’s available in your pantry, you can easily make this dish your own:
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Cheese: Cheddar is traditional, but don’t hesitate to use Monterey Jack, Gruyère, or sharp white cheddar to enhance the flavor profile.
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Cracker Topping: While buttery Ritz crackers are the hallmark of a classic Southern Squash Casserole Recipe, alternatives like panko breadcrumbs, crushed cornflakes, or even seasoned crackers can work just as well.
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Cream: Sour cream adds a nice tang, but Greek yogurt or a simple white béchamel sauce can be substituted if preferred.
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Onions: Sautéed yellow onions are ideal, but sweet Vidalia or even shallots offer excellent alternatives.
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Eggs: These provide structure, but for an egg-free version, try a cornstarch slurry or a plant-based egg substitute.
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Butter: Vegan butter or olive oil can be used for a dairy-free variation without losing richness.
Ingredients for Southern Squash Casserole
To make the perfect Southern Squash Casserole Recipe, you’ll need just a few humble yet flavorful ingredients that work together beautifully:
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Yellow Squash – This is the main star. Its tender texture and mild sweetness shine after baking.
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Onion – Brings a savory base and enhances the depth of flavor. Sautéing softens and mellows its bite.
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Eggs – Key for binding the casserole together so it holds up when sliced.
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Mayonnaise – Adds a creamy body and slight tang, creating a smooth texture.
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Sour Cream – Deepens the creaminess and adds a bit more richness.
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Shredded Cheddar Cheese – Mixed in and sprinkled on top, it gives the dish both flavor and that golden, bubbly finish. Sharp cheddar is especially good.
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Butter – Used to sauté vegetables and to coat the cracker topping for that irresistible crunch.
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Ritz Crackers – Crushed on top for a classic Southern crispy finish. Their buttery flavor is iconic to this recipe.
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Salt and Pepper – Essential for seasoning each layer of the casserole and balancing flavors.
Step-by-Step Instructions for the Best Southern Squash Casserole Recipe
Step 1: Preheat and Prep
To begin your Southern Squash Casserole Recipe, preheat your oven to 350°F (175°C). Lightly grease a 9×13-inch baking dish with butter or nonstick spray. This helps ensure the casserole doesn’t stick and makes for easy cleanup.
Step 2: Cook the Squash and Onion
In a large skillet over medium heat, melt 2 tablespoons of butter. Add the sliced yellow squash and chopped onion. Sauté for 10–12 minutes, stirring occasionally, until the squash is tender and the onions are translucent. Make sure to drain any excess liquid to avoid a watery Southern Squash Casserole.
Step 3: Make the Creamy Mixture
In a large bowl, whisk together 2 beaten eggs, ½ cup mayonnaise, ½ cup sour cream, and 1 cup of shredded cheddar cheese. Stir until smooth. Season with salt and pepper (about ½ teaspoon each) to enhance the base of this rich and savory Southern Squash Casserole Recipe.
Step 4: Combine and Layer
Gently fold the cooked squash and onion into the creamy mixture. Stir until everything is well coated. Pour the mixture into your prepared baking dish and spread it evenly.
Step 5: Add the Topping
Crush about 1 sleeve of Ritz crackers (around 30 crackers) and sprinkle evenly across the top. Melt 2 tablespoons of butter and drizzle over the cracker topping for that signature Southern golden crunch that makes this Southern Squash Casserole Recipe unforgettable.
Step 6: Bake
Bake for 30–35 minutes or until the top is golden brown and the edges are bubbling. Allow the casserole to rest for 5–10 minutes before serving to help it set properly.
How Long to Cook Southern Squash Casserole
For optimal texture and flavor, bake the Southern Squash Casserole Recipe at 350°F (175°C) for 30 to 35 minutes. The casserole is done when the topping is golden and the center is hot and set. If baking from chilled (after prepping ahead), add 10 extra minutes and cover loosely with foil to prevent over-browning.
Tips for a Perfect Southern Squash Casserole Recipe
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Choose smaller squash: They’re more tender and less seedy, giving you the ideal texture.
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Drain well: Removing moisture after sautéing keeps the casserole creamy—not soggy.
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Use sharp cheddar: This gives a bold flavor that balances the richness of the dish.
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Cracker texture matters: Aim for a rustic crunch—crumbly but not powdery.
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Add garlic: Sauté a clove with the onions for an extra flavor boost.
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Try extra seasoning: A pinch of paprika, cayenne, or fresh thyme can elevate the dish.
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Let it rest before slicing: This gives the casserole time to firm up and makes serving neater.
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Scale up with ease: Double the batch for gatherings—this Southern Squash Casserole Recipe is always a hit at potlucks and holidays.
Watch Out for These Mistakes While Cooking a Southern Squash Casserole Recipe
Even though the Southern Squash Casserole Recipe is simple and comforting, a few common mistakes can affect its final texture and flavor. Avoiding these can take your dish from good to truly unforgettable:
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Overcooking the squash during sautéing: When preparing squash for your Southern Squash Casserole, cook it only until just tender. It will continue to soften in the oven, and overcooked squash can lead to a mushy consistency.
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Skipping the draining step: Yellow squash naturally holds a lot of moisture. Failing to drain the sautéed squash and onion mixture thoroughly can result in a watery casserole, undermining the creamy texture this Southern Squash Casserole Recipe is known for.
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Using bland cheese: Mild cheddar won’t provide enough flavor to stand out. Choose sharp or extra-sharp cheddar to balance the creaminess and bring bold, savory depth to your Southern Squash Casserole.
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Forgetting to season properly: A well-seasoned base is key. Always taste the creamy filling before baking and adjust the salt and pepper accordingly. Under-seasoning is one of the most common issues with casseroles.
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Letting the cracker topping burn: The buttery Ritz cracker topping is iconic in any Southern Squash Casserole Recipe, but it can over-brown quickly. Check the casserole during the last 5 minutes of baking. If needed, loosely tent it with foil to prevent over-crisping.
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Overmixing the filling: Fold the squash into the creamy mixture gently. Overmixing can break down the squash slices and lead to a less desirable, overly soft texture.
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Not preheating the oven: This may seem basic, but starting in a cold oven leads to uneven cooking and a poorly set filling. Always preheat to 350°F (175°C) before baking your Southern Squash Casserole.
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Serving it too soon: It’s tempting to dig in right away, but letting the casserole rest for 5–10 minutes allows it to set properly and makes for cleaner servings.
What to Serve With Southern Squash Casserole Recipe
The beauty of a Southern Squash Casserole Recipe lies in its versatility—it can be the star of a casual weeknight meal or a trusted side at your next holiday gathering. Its creamy filling and golden, crunchy topping pair beautifully with both classic Southern mains and lighter veggie dishes.
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Fried Chicken
Nothing says Southern comfort like crispy fried chicken beside a warm scoop of Southern Squash Casserole. The crunch of the chicken plays perfectly with the creamy texture of the casserole. -
Grilled Pork Chops
Smoky, savory pork chops complement the buttery squash and cheesy topping. This combo turns any regular dinner into a Southern classic. -
Baked Ham
Whether it’s Easter, Christmas, or Sunday supper, baked ham adds a sweet, savory depth that highlights the subtle sweetness of the squash. -
Meatloaf
Pairing the Southern Squash Casserole Recipe with meatloaf creates a nostalgic, hearty dinner that delivers comfort with every bite. -
Roasted Turkey
This casserole is a favorite for holiday tables, holding its own next to juicy turkey and rich gravy. It’s also a perfect side for leftover turkey meals. -
Fresh Green Beans
Lightly steamed or sautéed green beans add a fresh, crisp contrast to the creamy squash filling, keeping the plate balanced and satisfying. -
Macaroni and Cheese
Go all-in on creamy comfort with a spoonful of baked mac and cheese next to your Southern Squash Casserole. It’s a dream team of gooey, cheesy deliciousness. -
Cornbread or Corn Muffins
Serve fluffy cornbread or savory corn muffins alongside your casserole to soak up every bit of its golden, buttery flavor. This Southern duo was made for each other.
Storage Instructions for Southern Squash Casserole Recipe
One of the reasons I love making this Southern Squash Casserole Recipe is how well it stores—making it perfect for prepping ahead or enjoying delicious leftovers throughout the week.
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Refrigerator: After your casserole has cooled completely, cover it tightly with plastic wrap or transfer to an airtight container. It stays fresh in the fridge for 3 to 4 days, and the flavors tend to deepen over time.
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Freezing: This Southern Squash Casserole can be frozen before or after baking. For unbaked storage, assemble the dish fully, then wrap it tightly with plastic wrap and foil. It will keep in the freezer for up to 2 months. When ready to enjoy, thaw it overnight in the fridge and bake according to the original recipe instructions.
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Reheating: Warm leftovers in a 350°F (175°C) oven for 15–20 minutes, covered with foil to prevent the cracker topping from over-browning. For quick reheats, individual servings can be microwaved for about 1–2 minutes.
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Make-Ahead Tip: You can sauté the squash and onions a day in advance and store them in the refrigerator. Then, simply mix everything and bake when needed—saving you prep time on busy days or during holidays.
Estimated Nutrition (Per Serving)
This Southern Squash Casserole Recipe is rich, cheesy, and comforting. Here’s a general nutritional estimate based on 1/8 of a standard 9×13″ dish:
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Calories: 280
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Fat: 20g
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Saturated Fat: 9g
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Cholesterol: 75mg
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Sodium: 400mg
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Carbohydrates: 15g
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Fiber: 2g
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Sugars: 4g
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Protein: 8g
Lighter Version Tip: To reduce calories and fat without losing the creamy texture, try using reduced-fat cheddar, Greek yogurt instead of sour cream, and a lighter mayo alternative.
Frequently Asked Questions About Southern Squash Casserole Recipe
1. Can I make Southern Squash Casserole ahead of time?
Yes, this Southern Squash Casserole Recipe is ideal for prepping in advance. You can fully assemble the dish up to a day before, cover it tightly, and refrigerate it. When you’re ready to bake, just pop it in the oven and add an extra 5–10 minutes of cook time if it’s coming straight from the fridge.
2. Can I use frozen squash instead of fresh?
While fresh yellow squash is recommended for the best texture and flavor in this Southern Squash Casserole Recipe, you can use frozen squash if needed. Just be sure to thaw it completely and drain off excess moisture to prevent the casserole from turning soggy.
3. Is this recipe vegetarian?
Yes, it can be. The Southern Squash Casserole Recipe contains no meat by default. Just ensure your cheese and crackers are vegetarian-friendly (some cheeses contain animal-based rennet) for a fully vegetarian version.
4. How do I keep the casserole from getting watery?
The key is to sauté the squash and onions thoroughly and drain any liquid before combining with the creamy ingredients. This step is crucial for maintaining the rich, thick texture that makes this Southern Squash Casserole so comforting.
5. Can I double the recipe for a larger group?
Absolutely! This Southern Squash Casserole Recipe scales beautifully. Use a larger baking dish or divide into two pans. Expect to extend the baking time slightly and look for bubbling edges and a golden-brown top as signs it’s done.
6. What are some topping alternatives to Ritz crackers?
If you don’t have Ritz crackers on hand or want to try something new, go for panko breadcrumbs, crushed cornflakes, or a mix of breadcrumbs and Parmesan cheese. Each adds its own unique crunch and flavor.
7. Can I make this casserole without eggs?
Yes, you can still enjoy this Southern Squash Casserole without eggs. Use a cornstarch slurry (1 tablespoon cornstarch mixed with 2 tablespoons water) or a vegan egg replacer to help bind the ingredients.
8. What’s the best cheese to use in this casserole?
Sharp cheddar cheese is the classic choice for this Southern Squash Casserole Recipe because it delivers bold flavor and melts beautifully. You can also experiment with Monterey Jack, Gruyère, or even smoked gouda for a deeper, more unique taste.
Conclusion
This Southern Squash Casserole Recipe is the kind of dish that feels like a warm hug from the kitchen—rich, creamy, and irresistibly comforting. Whether you’re serving it alongside a holiday ham, fried chicken, or simply enjoying it on a cozy weeknight, this casserole has a way of stealing the spotlight. I’ve returned to this recipe time and time again not just for its simplicity and flavor, but because it’s a guaranteed crowd-pleaser.
What makes this Southern Squash Casserole so special isn’t just the buttery cracker topping or the creamy filling—it’s the way it brings people together, evokes memories, and satisfies every bite. From family gatherings to Sunday suppers, it’s one of those timeless dishes that always disappears quickly and leaves everyone asking for seconds.
Once you try this from-scratch Southern Squash Casserole Recipe, you’ll see why it’s a Southern kitchen essential. And chances are, it’ll become a beloved staple in your own kitchen too.
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Southern Squash Casserole Recipe
Prep Time 15 minutes Cook Time 35 minutes Total Time 50 minutes Description
Ingredients
- yellow squash, sliced
- onion, finely chopped
- eggs, beaten
- mayonnaise
- sour cream
- sharp cheddar cheese, shredded
- butter (plus more for greasing)
- sleeve Ritz crackers (about 30), crushed
- Salt and pepper to taste
Instructions
- Preheat oven to 350°F (175°C). Lightly grease a 9×13-inch baking dish.
- In a large skillet, melt butter over medium heat. Sauté squash and onion until tender (about 10–12 minutes). Drain excess liquid.
- In a large bowl, mix eggs, mayonnaise, sour cream, shredded cheddar, salt, and pepper.
- Gently fold the squash mixture into the creamy filling.
- Pour into prepared baking dish and spread evenly.
- Sprinkle crushed crackers over the top.
- Drizzle with melted butter.
- Bake for 30–35 minutes until the top is golden and bubbly.
- Let rest 5–10 minutes before serving.